People with type 1 diabetes must test their blood sugar levels several times a day and inject insulin when it is needed. ... It is possible to treat type 1 diabetes by transplanting islet cells or even a whole pancreas to the patient from a donor.
In recent times Diabetes is one of the most widespread diseases, and its awareness is rapidly growing around the world. It is a common life-long condition and the number of children diagnosed with type 1 diabetes is increasing more day by day. For many, this means living with daily insulin injections and the possibility of long-term health damage
Type 1 diabetes is an autoimmune disease that results from T cell autoimmunity mediated destruction of the vast majority of insulin-producing pancreatic β-cells. In medical science the development of new therapies to control it and to preserve the remaining β-cell function is of great significance in managing patients with type 1 diabetes.
Those diagnosed with T1DM are relying on exogenous insulin.
Adipose tissue derived mesenchymal stem cells have been shown in many studies as potential cure for T1DM, which could not only address the need for β-cell replacement but also the regulation of the autoimmune response to cells which produce insulin. Mesenchymal stem cells are able to control T cell autoimmunity
The blood sugar will rise uncontrollably in both type of diabetics unless it is treated, and over time can lead to complications such as cardiovascular, liver and kidney disease (diabetic nephropathy), as well as circulatory problems that may require limb amputation, vision loss, blindness (diabetic retinopathy), and nerve damage (diabetic neuropathy)
People with type 1 diabetes must test their blood sugar levels several times a day and inject insulin when it is needed. Unfortunately, it can still be hard to keep the blood sugar level normal, even with regular injections.
Over time, a high level can cause serious damage to the heart, eyes, blood vessels, kidneys and nerves, whilst injecting too much insulin can lead to a level that’s too low (hypoglycaemia) and it can be fatal.
It is possible to treat type 1 diabetes by transplanting islet cells or even a whole pancreas to the patient from a donor. Transplants will enable the body to get back the control of blood sugar levels so that there will not be any more need for insulin injections. Islet transplantation is not very common, because the whole pancreas transplants involve major surgery and carry significant risk.In recent times , the donors is heavily outweighed by the demand and transplants require the immune system to be suppressed so that the new ‘alien’ organ is not rejected. Immunity suppressing drugs leave the recipient vulnerable to infections and often have side effects.
One of the biggest problems faced by islet transplantation is the lack of donors. Using s, own stem cells can be used in diabetes therapy than using donors so that we can avoid or, bypass all the complications, rejections and side effects.
Clinical trials inserting mesenchymal stem cells into type 1 diabetes patients take advantage of two assets these cells possess. Mainly, they have the potential to repair beta cells, and then, they can modulate the immune system by inhibiting the responses that lead to the autoimmune attack on pancreatic beta cells.
Stem cells are a part of a human body naturally, and they have the unique ability to find and repair the place of damage inside the system. It usually takes up to four months after the stem cells are injected into human organism during treatment to get fully develop. In the course of that time, a patient notices continuous new improvement. Moreover, there is also no risk of rejection or side effects since these stem cells from the patient’s body itself. The whole procedure is very quick, painless, simple and safe, and it is completed within only few hours. This approach increases beta cell function, in reducing or eliminating the requirement for exogenous insulin.
Stem Cell Therapy program to treat a variety of conditions, one of them being diabetes type 1. During stem cell treatment, a patient receives 200 – 300 million stem cells. This numbers of restored plain cells are not only covers daily losses, but also exceeds them by thousands of times, renewing almost 15 – 20 years worth. This causes symptoms of a disease to improve and the whole body and all of the organs become healthier and rejuvenated, because the new and active cells replace the old and damaged ones.